As the vendor should. The requirement noted in the req’s is .NET 4.7.2 (see here). But, newer versions should be fine. That being said, if your VBR server is running in a VM, it’s easy to test/verify. I would take a snapshot of the VBR server VM, upgrade/install .NET 4.8, then create a test backup job to see if it works as normal. After the upgrade, I’d also see if browsing other items - Repl jobs, job history, storage integration, anything else you’ve configured initially, looks ok. If all seems fine, delete & commit the VBR server VM snapshot. If this process isn’t something you’re willing to do, contact Veeam Support to verify .NET is supported.
Hope that helps.
Cheers!